What are bone marrow sinusoids?
Venous sinusoids in bone marrow are the site of a large-scale traffic of cells between the extravascular hemopoietic compartment and the blood stream. The wall of the sinusoids consists solely of a basement membrane interposed between a layer of endothelial cells and an incomplete covering of adventitial cells.
Where are sinusoids found?
Sinusoids are a special type of capillary that have a wide diameter. These are found in the liver, spleen, lymph nodes, bone marrow and some endocrine glands. They can be continuous, fenestrated, or discontinuous.
What blood flows through the sinusoids?
portal venous blood
Sinusoids, small blood vessels between the radiating rows of hepatocytes, convey oxygen-rich hepatic arterial blood and nutrient-rich portal venous blood to the hepatocytes and eventually drain into the central vein, which drains into the hepatic vein.
What is a sinusoid in the liver?
Sinusoids are low pressure vascular channels that receive blood from terminal branches of the hepatic artery and portal vein at the periphery of lobules and deliver it into central veins. Sinusoids are lined with endothelial cells and flanked by plates of hepatocytes.
Why does bone marrow have sinusoid capillaries?
Organs such as the liver, spleen, and bone marrow contain blood vessel structures called sinusoids instead of capillaries. Discontinuous sinusoid endothelium contains even larger pores that allows blood cells and larger proteins to pass between the vessels and surrounding tissue.
Why are there sinusoid capillaries in bone marrow?
What is the role of sinusoid of liver?
In the liver the blood from the portal vein flows through a network of microscopic vessels called sinusoids in which the blood is relieved of worn-out red cells, bacteria, and other debris and in which nutrients are added to the blood or removed from it for storage.…
What does the liver secret?
The liver secretes bile, a digestive fluid; metabolizes proteins, carbohydrates, and fats; stores glycogen, vitamins, and other substances; synthesizes blood-clotting factors; removes wastes and toxic matter from the blood; regulates blood volume; and destroys old red blood cells.